Recently, work has been going on at Yale W-4PiSMSN Whole Cell 4Pi single marker switching nanoscopy graphical abstractUniversity, the Gurdon Institute at Cambridge University and Purdue University with funding provided by the Wellcome Trust Research Programme to develop a high resolution widefield microscope capable of imaging entire cell structures at once. This group has published an article in the journal Cell which describes the W-4PiSMSN (Whole Cell – 4Pi single marker switching nanoscopy). In this article they show the results of imaging the endoplasmic reticulum (ER), bacteriophages, mitochondria, nuclear pore complexes, primary cilia, Golgi-apparatus-associated COPI vesicles, and mouse spermatocyte synaptonemal complexes. The instrument includes two Boston Micromachines Multi Deformable Mirrors which are used to optimize the optical wavefront due to aberrations in both the instrument and biological sample. We’re so excited about this incredible breakthrough and I am sure you will be too!!!!
The full article, images and videos can be found here:http://www.cell.com/cell/fulltext/S0092-8674(16)30745-0
Defense TechConnect Conference and Expo: Fun in the Sun with the MRR
Last week I was fortunate enough to be able to parade BMC’s Modulating RetroReflector (MRR) in front of multiple audiences affiliated with the Defense community at the Defense TechConnect (DTC) Conference and Expo in Tampa, Florida.
# Adaptive Optics Scanning Laser Ophthalmoscope 11.01.2018Read more
MiFoBio 2018: AO Microscopy in Action
Recently, Boston Micromachines sponsored MiFoBio (Functional Microscopy in Biology), an event that brought together the microscopy community, academics and professionals alike, to attend courses and workshops that explored the understanding and current trends of biological imaging.
# Adaptive Optics Scanning Laser Ophthalmoscope 10.16.2018Read more