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Boston Micromachines Awarded Grant from NEI to Further Adaptive Optics Retinal Imaging Instrument
BMC Develops Adaptive Optics Scanning Laser Ophthalmoscope for Earlier Detection and Treatment of Retinal Diseases

Cambridge, Mass., March 13, 2013 – Boston Micromachines Corporation (BMC), a leading provider of MEMS-based deformable mirror (DM) products and adaptive optics systems, announced today that it has been awarded a $1.2M  Phase II Competing Renewal Small Business Innovation Research Grant (SBIR) from the National Eye Institute (NEI) of the National Institutes of Health (NIH). 

The grant will enable BMC to fabricate a next-generation Adaptive Optics Scanning Laser Ophthalmoscope (AOSLO), a high-resolution, high-contrast retinal imaging system which includes a MEMS deformable mirror for wavefront correction and was built in collaboration with the Indiana University School of Optometry. A primary goal of the project is to demonstrate the usefulness of AOSLO imaging as a quantitative tool in clinical studies of eye disease such as diabetic retinopathy and age-related macular degeneration.  As part of this development, BMC will develop imaging, ergonomic, and software enhancements over the current AOSLO design. This project will also be a collaboration with Dr. Stephen Burns and Indiana University.

As part of the program BMC will install and support the AOSLO instrument at the Beetham Eye Institute (BEI) of the Joslin Diabetes Center for an observational pilot study. “One of our goals in the study is to examine AOSLO images taken from eyes of patients with and without diabetes and across a wide range of diabetic eye complication severity.  This will allow us to characterize neural and vascular cellular changes in the diabetic retina and may give us new understanding of how diabetic eye complications develop and should be treated.” said Dr. Jennifer K. Sun, Ophthalmologist in Beetham Eye Institute at Joslin.

 “We are pleased with the continued support we have received from the NEI,”said Paul Bierden, president of Boston Micromachines Corporation. “The AOSLO has proven to produce exceptional images of important retinal structures which should have a profound effect on the diagnosis and treatment of eye diseases.”